Pope Francis has made a “pressing appeal” against a “spiral of violence” after Iran’s missile and drone attack on Israel, warning of a potential regional conflagration, AFP reports.

“I make a pressing appeal for an end to any action which could fuel a spiral of violence that risks dragging the Middle East into an even greater conflict,” the Argentinian pontiff declared.

“I am praying and following with concern, but also pain, the news that has come in recent hours about the worsening situation in Israel due to Iran’s intervention,” the pope told worshippers.

“No one should threaten the existence of others. All countries must, however, side with peace and help Israelis and Palestinians to live in two states, side by side and in security,” he said. “That is their right.”