NEW DELHI: The World Health Organ­isation has issued an alert warning against the use of two Indian cough syrups blamed for the deaths of at least 20 children in Uzbekistan.

WHO said the products, manufactured by India’s Marion Biotech, were “substandard” and that the firm had failed to provide guarantees about their “safety and quality”.

The alert, issued on Wednesday, comes after Uzbekistan authorities said last month at least 20 children died after consuming a syrup made by the company under the brand name Doc-1 Max.

India’s health ministry subsequently suspended production at the company and Uzbekistan banned the import and sale of Doc-1 Max.

The WHO alert said an analysis of the syrup samples by the quality control laboratories of Uzbekistan found “unacceptable amounts of diethylene glycol and /or ethylene glycol as contaminants”. Diethylene glycol and ethylene are toxic to humans when consumed and can prove fatal.

Authorities in Uzbekistan say 20 children died last month after consuming a syrup imported from India

“Both of these products may have marketing authorisations in other countries in the region. They may also have been distributed, through informal markets, to other countries or regions,” WHO said.

The products were “unsafe and their use, especially in children, may result in serious injury or death”, it said. Marion Biotech officials could not be reached immediately for comment.

It is the second Indian drugmaker to face a probe by regulators since October, when the WHO linked another firm’s medicines to a spate of child deaths in Gambia.

Published in Dawn, January 13th, 2023