Three Zebra fish, which were injected with a green fluorescent protein gene from a jellyfish and a red gene from a sea anemone into its embryo, are seen glowing under ultra-violet light in Singapore, 24 May 2001. — AFP Photo

PARIS, April 17, 2013 - One of the world's most popular aquarium fishes on Wednesday joined the rat, the mouse, fruitfly and nematode worm in the roll call of creatures whose DNA has been sequenced to help fight disease among humans.

A consortium of researchers unveiled the genome of the zebrafish in the British journal Nature, declaring it made a vital model for pinpointing faulty genes.

The tiny striped fish - Danio rerio in Latin - has 26,000 genes, 70 percent of which are shared with humans.

Eighty-four percent of genes known to be associated with human disease have a zebrafish counterpart.

The fish has a brief life cycle and in the embryonic stage is transparent, which makes it highly useful in the lab.

The zebrafish has already unlocked insights into cancer and heart disease and advanced knowledge of muscle and organ development, including genes implicated in muscular dystrophy.

“We can readily create variations in their genome that are relevant to human health and disease. This has allowed a greater understanding of gene function and the finding of new targets for drug treatments,” said Leonard Zon of the Children's Hospital of Boston, Massachusetts.

“Several small molecules discovered using the zebrafish system have recently entered clinical trials,” he said in a press release.

“The availability of the genome sequence, coupled with the rapid expansion of disease models and chemical screening ability, ensures that the zebrafish system has a major place in biomedicine.”

Opinion

Editorial

Business concerns
Updated 26 Apr, 2024

Business concerns

There is no doubt that these issues are impeding a positive business clime, which is required to boost private investment and economic growth.
Musical chairs
26 Apr, 2024

Musical chairs

THE petitioners are quite helpless. Yet again, they are being expected to wait while the bench supposed to hear...
Global arms race
26 Apr, 2024

Global arms race

THE figure is staggering. According to the annual report of Sweden-based think tank Stockholm International Peace...
Digital growth
Updated 25 Apr, 2024

Digital growth

Democratising digital development will catalyse a rapid, if not immediate, improvement in human development indicators for the underserved segments of the Pakistani citizenry.
Nikah rights
25 Apr, 2024

Nikah rights

THE Supreme Court recently delivered a judgement championing the rights of women within a marriage. The ruling...
Campus crackdowns
25 Apr, 2024

Campus crackdowns

WHILE most Western governments have either been gladly facilitating Israel’s genocidal war in Gaza, or meekly...