Two teenagers were killed while eight others injured in an explosion in Quaidabad area of the metropolis on Friday night, according to police and hospital officials.

Following the blast, police and rescue teams rushed to the site and shifted the injured to Jinnah Postgraduate Medical Centre (JPMC) for treatment.

JPMC Executive Director Dr Seemi Jamali confirmed the death of two persons, saying they succumbed to injuries on their way to the hospital. She said the hospital received eight injured, of which three are in critical condition.

Both deceased were teenagers, one of them was identified as Papu Mushtaq, 16, while the identity of other deceased aged 18 years remained unknown.

The injured men were identified as Rasheed, 18, Mushtaq, 22, Haq Nawaz, 55, Siddiq 55, Araslan, 35, Allah Ditta, 25, Qamar Abbas, 28, and Shahab, 26.

Karachi police chief Ameer Sheikh said some vendors at a makeshift market were selling fruit and other items of daily use near the Quaidabad flyover when the bomb went off nearby.

The senior officer said that the exact nature of the explosion was being determined. The law enforcement officials cordoned off the area soon after the attack and collected evidence for an investigation into the incident and to ascertain the nature of the blast.

Shah Latif Town police said that some unidentified thing present under the fruit cart exploded near Aman Hospital adjacent to the deputy commissioner’s office.

DSP Malir City Ali Hassan also said that a cart belonging to a fruit vendor present near the DC office "had some unknown things present under it which exploded".

He too could not confirm the cause of the blast but said that a Bomb Disposal Unit (BDU) had been called to the site which was busy assessing another explosive device recovered from the site of the blast, said to be planted within a "tiffin box", DawnNewsTV reported.

The surrounding area experienced a breakdown of electricity following the blast, which is yet to be restored, according to DawnNewsTV.

Meanwhile, Sindh Chief Minister Murad Ali Shah was quick to take notice of the incident and sought a report from the Additional IG Karachi and directed that all possible assistance be given for the treatment of the injured persons.

Governor Imran Ismail also took notice of the blast and sought a report from IG Sindh.

There has been no immediate claim of responsibility from any group.