LOS ANGELES: “Wreck-It Ralph,” Disney's  animated film about a video game character who destroys everything in his path, made history on Sunday after grossing $49.1 million in ticket sales to lead the weekend box office, the highest-grossing opening weekend in Disney animation history.

The tally for “Wreck-It-Ralph, which featured the voices of John C. Reilly and Jane Lynch, hammered the Denzel Washington film “Flight,” which generated ticket sales of $25 million at US and Canadian theaters, according to studio estimates.

The critically acclaimed Iran hostage thriller “Argo,” last week's box office leader, was third, generating $10.2 million in sales. Directed by and starring Ben Affleck, “Argo” has totaled $75.9 million in its three weeks in movie theaters.

Walt Disney Co released “Wreck-It Ralph.” “Flight” was distributed by Paramount Pictures, a unit of Viacom Inc . Warner Bros., a division of Time Warner Inc , distributed “Argo.”