An Israeli airstrike has killed at least 29 Palestinians, including children, in a house in Shujaiya in Gaza City, Reuters reports citing local health authorities.

Medics said dozens of others were wounded in the attack that hit a multi-floor residential building in the eastern suburb of Gaza City. Many were still believed to be missing and trapped under the ruins of the building. The strike damaged several other houses nearby, medics said.

The Israeli military said in a statement it struck a senior Hamas militant responsible for planning and executing attacks from Shujaiya in northern Gaza, whom it did not identify. The military said several steps were taken before the attack to mitigate harm to civilians.