Four people, including three members of the Hazara community, were killed and two others were injured when unidentified gunmen opened fire on their vehicle in Quetta's Kuchlak area on Sunday evening.
The members were "targeted" on their way from the Chaman border crossing at the Pak-Afghan border, said police official Zahoor Khan.
Two women travelling in the car were injured and transferred to Quetta's Civil Hospital for treatment, Khan told DawnNews, adding, "The incident seems to be an act of targeted killing."
The suspects sped away on their motorcycles after opening fire, Khan said.
Moments later, police officials and law enforcement agencies' personnel arrived at the site of the incident as investigations into the shooting were underway.
In the aftermath of the attack, traffic at the busy Kuchlak Bazar was jammed for one hour.
Chief Minister Balochistan Nawab Sanaullah Zehri strongly condemned the incident and directed the police to apprehend the culprits involved.
"Terrorists will not be spared," the chief minister said in a statement issued to the press on Sunday evening.