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An Israeli Iron Dome missile is launched near the city of Be'er Sheva, southern Israel, Nov. 17, 2012.   — Photo by AP

GAZA CITY: Israeli strikes on Sunday killed 23 Palestinians including 14 women and children in the bloodiest day of its Gaza bombing campaign, the Hamas-run health ministry said.

Nine children, five of them babies and toddlers, and five women were among the victims in violence that raised the overall number of Gazans killed to 69 in around 100 hours of relentless Israeli air strikes.

The attacks came as diplomatic efforts intensified to broker an end to the bloodshed which began on Wednesday and has also cost the lives of three Israelis and injured more than 50, according to medical sources.

By far the bloodiest strike was in northern Gaza City where a missile levelled a three-storey building, killing nine members of the Al-Dallu family, five of them children, and two other people, medics said.

Health ministry spokesman Ashraf al-Qudra named the dead as policeman Mohammed al-Dallu, 35, Suheila al-Dallu, 50, Samah al-Dallu, 22, and five children: Jamal and Sara, whose ages were not immediately available, five-year-old Yussef, two-year-old Ranin, and 11-month-old Ibrahim.

The body of another woman from the same family was also pulled from the rubble but her identity was not immediately clear.

The other two victims, who lived next door, were named as Amina Mattar al-Muzzana, 83, and Abdullah Mohammed al-Muzzana, 22, Qudra said.

The Israeli army had no immediate comment on the strike, saying only that the air force had hit “a few targets in northern Gaza City”.

Shortly afterwards, six more Palestinians were killed in four separate strikes, two in Gaza City, one on the Jabaliya refugee camp and one on the Nuseirat refugee camp in central Gaza.

In Gaza City, Sami al-Ghafir was killed in a raid on the eastern Shejaiya neighbourhood, and Mohammed al-Awf was killed in the north of the city.

The strike on Jabaliya killed Suheil Hamada and his son Moamin as they were driving a water delivery truck through the camp.

And an early-evening strike on Nuseirat killed two men, Aatiya Mubarak and Hossam Abu Shawish, the emergency services said.

Earlier strikes across the strip killed six more Palestinians, four of them children.

At around 2:00 am (0000 GMT) strikes on the northern town of Beit Hanun killed two toddlers, three-year-old Tamer Abu Saeyfan and his one-year-old sister Jumana.

Several hours later, 18-month-old Iyyad Abu Khusa was killed in a strike east of Bureij refugee camp in central Gaza. His two brothers, aged four and five, were critically wounded in the raid, Qudra said.

Medics later reported finding under the rubble of a house in eastern Gaza City the body of a woman who had been killed in a strike earlier in the morning. They named her as Nawal Abdelaal, 52.

And in the late morning an air strike on a small house in the beachfront Shati refugee camp in Gaza City killed 13-year-old Tasneem al-Nahal and Ahmad al-Nahal, 25, both from the same family.

The bloodshed has killed 69 Palestinians and injured more than 600 since an Israeli air strike which killed a top Hamas militant kicked off the Jewish state's military campaign against Gaza.

Three Israelis have been killed and more than 50 injured, a spokesman for the Magen David Adom emergency services told AFP. The army said 10 of them were soldiers, one of whom was severely hurt.

On Sunday, nine people were injured by rockets in southern Israel, one of them seriously and two moderately.

So far, the military says it has struck more than 1,132 targets in the Gaza Strip, without saying how many strikes it had carried out.

In the same period, 544 rockets fired by Gaza militants have stuck southern Israel, and another 302 have been intercepted by the Iron Dome missile defence system.

For more in-depth coverage on the Gaza-Israel conflict including stories, features, analysis and multimedia, visit: In-depth coverage: Gaza-Israel conflict