SAN FRANCISCO: Brain implants have long been trapped in the realm of science fiction, but a steady trickle of medical trials suggests the tiny devices could play a big part in humanity’s future.

Billions of dollars are flowing into a clutch of specialist companies hunting for treatments for some of the most debilitating ailments. And pioneering studies have already yielded results.

In May, a Dutchman paralysed in a motorcycle accident regained the ability to walk thanks to implants that restored communication between his brain and spinal cord.

That experiment was one of several eye-catching trials that have helped spark a huge buzz around the industry.

According to Unesco, investors have poured over $30bn into neurotechnology

In the decade to 2020, investors poured more than $30 billion into neurotechnology more widely, according to Unesco.

And the money has continued to flood in thanks, in part, to rapid improvements in artificial intelligence (AI), used by researchers to interpret the data from the implants.

Tech titan Elon Musk has refocused some energy on his Neuralink firm after it received permission in May to test its implants on humans, helping it to raise $280 million in funding.

And other firms with less prominent bosses are proliferating, offering hope for sufferers of ailments from rare nerve diseases to severe epilepsy.

‘Turning point’

Synchron, a company formed more than a decade ago, raised $75m this year with backing from the likes of Microsoft co-founder Bill Gates and Amazon’s Jeff Bezos.

The firm got permission from the US authorities in 2021 to test its implant, and has since rolled it out to nine people with Amyotrophic Lateral Sclerosis (ALS) — the motor neurone disease that physicist Stephen Hawking suffered from.

Its implant allows patients to use messaging apps or browse online using only eye movements and thoughts.

One of the big selling points is that, unlike other implants, it does not require invasive surgery.

The first goals of the Synchron test, said Dr David Putrino, who oversaw the medical trial at Mount Sinai Hospital in New York, were to make sure the implant was safe and could monitor the brain over long periods.

On both fronts, he said, the trial had been a success.

Synchron founder Tom Oxley thinks the technology, known as brain-computer interface (BCI), is now at a “turning point”.

The industry must aim to make the implants widely accessible, he said.

Brain attack

There are still pretty hefty impediments before that can happen, not least that the most powerful results often come from the most invasive implants.

For example, a patient in the US, Ian Burkhart, who was left paralysed from the neck down after a diving accident, said that getting an implant that allowed him to control his arms and hands again was a “magical moment”.

But he was only ever able to do that in a lab and the implant, known as a Utah array, was far from comfortable.

Published in Dawn, August 21st, 2023