The world's first human challenge trial in which volunteers were deliberately exposed to Covid-19 to advance research into the disease was found to be safe in healthy young adults, one of the companies running the study hassaid.

The data supports the safety of this model which could theoretically provide a “plug and play” platform for testing therapies and vaccines using the original Covid-19 strain as well as variants of the virus, Open Orphan, which carried out the study, said in a statement.

The trial infected 36 healthy male and female volunteers aged 18-29 years with the original Sars-CoV-2 strain of the virus and closely monitored them in a controlled quarantined setting. They will be followed up for 12 months after discharge from the quarantine facility, according to Reuters.

No serious adverse events occurred, and the human challenge study model was shown to be safe and well-tolerated in healthy young adults, the company said.

Opinion

Editorial

Mixed messaging
Updated 02 Jun, 2026

Mixed messaging

It is fair to ask how these actions fit into a strategy that is supposedly aimed at reaching a negotiated settlement.
Sugar: the bitter truth
02 Jun, 2026

Sugar: the bitter truth

THEY are at it again. Politically powerful sugar mill owners are back with their demand seeking permission to export...
Uphill battle
02 Jun, 2026

Uphill battle

A DISPUTE has broken out between Karachi’s political representatives over illegal encroachments on the city’s...
Budget concerns
Updated 01 Jun, 2026

Budget concerns

Mistaking IMF compliance for sound economic management is what is driving the economy into deeper stagnation.
Gaza’s tragedy
01 Jun, 2026

Gaza’s tragedy

HISTORY may record this as one of the most brazen deceptions of our time. President Donald Trump’s so called Board...
New sports policy
01 Jun, 2026

New sports policy

BETTER sense has prevailed with a new national sports policy set to be rolled out, thus preventing a clash between...