Genetic map can help better identify tumors: study
CHICAGO: Researches have developed a genetic mapping tool which could allow for better diagnosis and treatment of common tumours, according to a study published on Monday.
The study was focused on mapping the molecular features of the most common and deadly primary brain tumour so that its various subtypes could be recognised in magnetic resonance imaging (MRI) scans.
But the same method could be used to better identify other tumour types, said lead author Michael Kuo of the University of California at San Diego.
“We found a way to allow MRIs to give us detailed molecular information about these tumours,” he said in a telephone interview.
“In the past the only way you’d get it is by doing invasive biopsies and running expensive tests that aren’t standardized.” Kuo and his team used biopsy samples to map the genetic structure of different subtypes of the tumours and compared them to MRI scans from the patients who had provided the biopsy tissue.
They were able to find specific features of the tumour subtypes that could be identified in the highly detailed image, potentially eliminating the need for a biopsy.
“Now you can look at the image and say here is the tumor, here it is in the brain, but also these are some of its molecular features,” he said, adding that his group published a paper last year showing how this method could work on another type of tumour using a different imaging type.
“It’s a robust and scalable technology,” he said.
“It can work with different imaging technologies such as CAT scans and MRIs and it looks like it works in different tumor types such as liver cancer.”
