Demonstrators wearing masks of Italian Prime Minister Silvio Berlusconi (R) and the leader of the Northern League Umberto Bossi pose with placards reading “Silvio, change the panorama” during a demonstration “Reconstruction. For the name of the Italian people” organized by the let-wing Democratic Party (PD) on November 5, 2011 in Rome. -AFP Photo

ROME: Tens of thousands of opposition activists have demonstrated in central Rome for Premier Silvio Berlusconi's ouster.

Democratic Party leader Pierluigi Bersani told the crowd that his party was prepared to work with other opposition groups to lead a new government.

Berlusconi's grip on power has been weakened by the ongoing sovereign debt crisis and infighting in his coalition that has prevented clear measures.

Italy's borrowing costs to service its enormous public debt at 120 per cent of GDP have been rising since the summer.

The protesters, who arrived on buses and trains from throughout Italy, were joined by center-left politicians from France and Germany, as well as a group of topless female demonstrators from Ukraine known as Femen.