The 21-year-old world number one is 11 years Agassi’s junior, but he showed no signs of sentiment in his victory over the seven-time grand slam champion in front of a capacity 10,500 crowd.
Agassi made the early running before Hewitt fought back in an hour long opening set that was marked by five breaks of serve.
The Australian broke decisively for 6-5 and served out the set to love.
The second set was equally as competitive until Hewitt applied enough pressure to break his opponent to love at 3-3.
The top seed was ruthless thereafter and didn’t allow Agassi another game.
Hewitt now has a winning 4-2 record over Agassi in career matches, having won their last three contests.
Results (prefix number denotes seeding):
Quarterfinals: 1-Lleyton Hewitt (Australia) beat 6-Andre Agassi (U.S.) 7-5 6-3; 8-Juan Carlos Ferrero (Spain) beat Wayne Arthurs (Australia) 6-4 7-6 (7-4); 16-Carlos Moya (Spain) beat Rainer Schuettler (Germany) 7-6 (7-3) 6-1
MANHATTAN BEACH (California): Defending champion Lindsay Davenport ended the run of Eleni Daniilidou in the quarterfinals of the Los Angeles Open Friday as top seeds Serena Williams and Jennifer Capriati suffered stunning upset losses.
Results:
Quarterfinals: 3-Lindsay Davenport (U.S.) beat Eleni Daniilidou (Greece) 7-6 (7-2) 6-2; Ai Sugiyama (Japan) beat 2-Jennifer Capriati (U.S.) 6-3 6-3; 4-Jelena Dokic (Yugoslavia) beat Rita Grande (Italy) 6-4 6-1; 12-Chanda Rubin (U.S.) beat 1-Serena Williams (U.S.) 6-2 4-6 7-5—Reuters