Counterproductive and self-defeating: KARACHI FILE
By A. B. S. Jafri
AS the country’s largest city, Karachi owes it to itself to be a trend-setter, a role model. Last week was not the one that would do it proud. Medical staff, that is postgraduate doctors, of Jinnah Postgraduate Medical College, went on strike. It is something that leaves one speechless, numb. Patients were left to their aches and pains. It defies belief that normal human beings, holding responsible positions, would do such a thing under any circumstances.
It is generally believed that nearly five centuries before Christ, a Greek man of medicine, Hippocrates (c460-357 BC) laid down the principle that a doctor shall consider as inviolable the commitment to attend to his/her patient. One should expect postgraduate doctors to be doubly conscious of their primary and ultimate responsibility that is to attend to the needs of the patient in their charge.
Whether the demands/ grievances/complaints of the striking doctors were genuine or not is irrelevant, as far as the categorical imperative of the ethics of the medical profession and service is concerned. Postgraduate doctors are expected to set an example for their junior brothers and sisters in the profession. Whether or not the law has anything to say on this subject is perhaps unclear. It is about time the law was made able to take cognizance of such situations.
Be that as it may, there is a clear moral dimension to this kind of contingency. Perhaps even more delicate is the issue from a humanitarian point of view. Can one condone the fact that a person — man, woman, child — has been left in pain by those who are bound to attend to him/her? Those who visit a hospital, or are admitted to its wards, have a wholly unqualified right to complete attention from medical staff. Period. Striking doctors’ conduct remains irredeemable. How serious were the doctors’ grievances would remain a subordinate and subsidiary factor. There may be a dozen different ways in which to air those grievances and agitate for their acceptance. Abandoning patients to their pain and agony cannot be a legitimate tactic, strategy or instrument. This comes perilously close to an act of inhumanity. How would one look at a possible death resulting from abrupt denial or refusal of medical treatment? This is a question that the doctors going on strike have still to answer.
No less unsettling is the question of political agitations in the streets. Last Friday platoons of the alliance of the religious parties took to the streets in Karachi. It is hard to feel very comfortable about mobilizing the Friday prayer assemblage for rank partisan political purposes. One would perceive something of indelicate opportunism in turning Friday prayer gatherings into occasions for political warfare.
By and large, the people of Pakistan are unhappy over what they see as a distinct element of indiscriminate intolerance towards Muslims in the policies adopted by a superpower. International news agencies report extraordinary measures being taken, exclusively targeting Muslims. Even if allowance is made for some measure of exaggeration or sensationalization, there remains sufficient ground to feel aggrieved and hurt.
Public sentiment must be given unhindered expression. There can be no question about the public right to express disapproval and concern. It is there and must be respected. But is street agitation the most effective and the most elegant way of rejecting what is seen as wrong and demanding that the wrongs be righted? For most sober and sane people the answer to this undeniably pertinent question would be in a firm negative.
The attempt to make political mileage out of the issues the Friday agitation in Karachi (also elsewhere in Pakistan) was focusing on, cannot be seen with much equanimity. Public peace and maintenance of order in the streets should be treated as a basic requirement of civilized living. People drawn out of the avenues of normal life and urged or instigated to disrupt order, leaves one with the feeling that this kind of protest demonstration is lowering the level of political action. This only detracts from the dignity of the message sought to be conveyed to the party whose action is deemed as unfair and unworthy.
Because of its special status, Karachi becomes the first choice of those who believe street rumpus can be pressed into political service. Neither the doctor’s strike nor the noisy and disorderly street agitation of the religious parties can be approved. Besides, it needs to be noted that the religious party alliance is now very much in the business of hard-nosed politics. If Karachi is to maintain its high profile, it has to remain dignified even when the public sentiment should be one of intense anger and deep anguish.
Noisy street agitation is a dangerous political weapon. It is not always easy to keep such agitations within the bounds of peace and decency. Karachi has seen protest processions turning into riotous situations. We have seen buses put on fire, private cars stoned, newspaper offices ransacked, banks looted. Hand-to-hand fights in the wake of protest demonstrations are not unknown.
This kind of disorder is a luxury this prime centre of business, finance and industry cannot afford to indulge in. It sends the wrong signals to the outside world from where we expect investment, trade, profit and support to national economy. It is with great difficulty that Karachi has retrieved its position as a safe place for investment. Street rumpus does this city no good and it does not really advance the cause in whose name angry processions are taken out.


The physician in the pharmaceutical industry
By Dr A. Atif Mirza
A CAREER working for a drug company is an alternative that is too often overlooked by physicians. Practising physicians are needed by the research-based pharmaceutical industry in many areas, ranging from the pre-clinical screening of new drugs through the marketing of the approved products.
The needs of the pharmaceutical industry are deceptively simple. Research-based drug firms need to collaborate and cooperate with leading clinical investigators to conduct well-controlled, state-of-the-art drug trials.
An ongoing relationship with academicians and clinical consultants satisfies the immediate, short-term needs of the industry by providing second opinions on the uses of certain investigational and marketed drugs or on a drug development plan.
Practising physicians can also act as spokespersons for their peers concerning particular drugs or treatment approaches.
Academic consultants, however, are important as medical educators for industry physicians, who are required to remain in touch with current trends in medical practice and who frequently arrange for clinical orientation programmes.
On a long-term basis, the pharmaceutical industry always requires scientific and medical professionals to affirm the efficacy and safety of medications in the clinical research pipeline; to ensure the medical validity of scientific, educational, and promotional information; and to assess the medical impact of drugs proposed for licensing or for development through a new drug application (NDA).
The pharmaceutical industry has much to offer a physician; it’s more than just trading a stethoscope for a briefcase and a pen or a lab coat for a business suit. It’s being a team player at all times and learning to access your creativity on demand. The rewards include opportunities for enrichment through continuing medical education programmes; attendance at medical and scientific meetings; availability of textbooks and journal subscriptions as needed, and excursions to marketing and management meetings as part of the job.
For a pharmaceutical physician (PP), all this has engendered a somewhat different life-style than he had become used to as a clinician. There have been predictable hours and dependable vacations even at times of year when he would previously have had to fight “tooth and nail” to get some free time.
Although he has the opportunity to do so, he may no longer be required to attend hospital rounds. He also has to give up the dubious privilege of answering emergency calls. Also, regular pay is not something hard to get used to. He can also practise medicine by maintaining a clinic or being a part of a teaching faculty on a part-time basis or as arranged with his employers.
As a member of the companies sales-force education team, he is often called upon to create a meaningful way of communicating medical concepts and rationales for treatment to sales representatives.
The pharmaceutical industry generally recruits practising physicians by advertising career opportunities in leading newspapers. Word-of-month, bulletin board postings at national meetings, and the use of executive recruiters also provide excellent candidates to fill industry positions.
Once you’re a member of the industry, further career mobility is possible within your firm if another position is more appealing. There are ample opportunities in the field of sales and marketing, research and development and training, besides the medical department. If he proves his worth working in a company he can also be promoted to regional level, working in the regional headquarter or the therapeutic areas as an expatriate employee and also head the company.
ROLES: Medical marketing and medical services are two areas in which physicians are employed as full-time managers, but with an opportunity to use their medical skills. Physicians in these areas ensure that promotional and educational materials put out by the various parts of a firm’s marketing division are medically valid and reflect current and accepted medical opinion. An industry physician also will assist in training the sales representatives and may be involved in conducting Phase IV drug studies.
In research and development (in a multinational pharmaceutical industry), physicians generally are included throughout the drug development process, from Phase 0 (the pre-clinical evolution and screening of new compounds) to the comprehensive Phase III clinical trials conducted in support of an NDA. Industry physicians are then needed to provide to the health authorities overall safety and efficacy evaluation and the medical rationale for approval of a new drug.
The physicians of the pharmaceutical industry also become part of the team responsible for ongoing safety surveillance and documentation of a drug’s approved uses. These Phase IV studies and all drug safety studies of marketed drugs require a physician’s direction.
Although referred to variously as a company’s medical affairs, professional services, or medical services department, all are responsible for answering queries by healthcare professional about a firm’s products. Members of these departments are also asked to ensure the accuracy and appropriateness of product information and medical concepts used in the training of the sales force. In essence he is the custodian of ethics and ensures that these are fully incorporated in all fields.
The following gives the outline of the job requirement of a PP:
Prerequisite: up-to-date knowledge of pharmacology and therapeutics; discovery of medicines; pharmaceutical development; toxicity testing; regulatory, legal and ethical issues; development of medicines; clinical trials; medical statistics; safety of medicines; regulatory affairs; information, promotion and education; economics of healthcare and function of the medical department.
As can be seen from the above, the pharmaceutical physician is a very important member of the team running the pharmaceutical industry. He can ensure the setting, maintenance and improvement of standards in pharmaceutical medicines needed for the benefit of patients and the health of the community.
Faculty of PP is being established in the UK (Royal Colleges) and other European countries. It is also under serious consideration by the American association. Once these are established and with university level courses being run already by different universities working up to a diploma examination, this faculty shall be established very soon.
Pharmaceutical physicians have formed a body internationally known as the International Federation of Associations of Pharmaceutical Physicians (IFAPP). Their mission “is to promote pharmaceutical medicine by enhancing the knowledge, expertise and skills of pharmaceutical physicians worldwide, thus leading to the availability and appropriate use of medicines for the benefit of patients and society.”
Pakistan having its own association (Pakistan Association of Pharmaceutical Physicians (PAPP) is a member of the international body.
The writer is the vice-president of PAPP.

