Menace of diabetes highlighted
By Shamsul Islam Naz
A seminar was held at a local hotel last Sunday for updating the knowledge of general practitioners and family physicians about the latest advancements and research made in the treatment of diabetes. It was attended by a good number of physicians from all over the country.
Speakers read out well-prepared papers on various causes of the menace of diabetes, its symptoms and effects on human health. However, there were only 167 persons present in the hall a majority of whom were sale representatives, executives and promoters of pharmaceutical companies and attendants of consultants.
One is wonder struck by the poor attendance in a city which is planning to launch another medical college and which has thousands of students and hundreds of teachers. In the Agriculture University alone, out of 458 teachers, there are 255 Ph.Ds whereas in the National Institute of Biotechnology and Genetic Engineering, the Nuclear Institute of Agriculture and Biology, the Ayub Agriculture Research Institute and the Forest Research Institute, there is also a sizable strength of teachers and students all of whom would have benefited from such an illuminating gathering.
Its organizers admit that they had arranged 250 chairs in the hall and that 516 persons had been registered. Many of them preferred to stay out and wait for lucky draw prizes arranged for attracting doctors and students. Throughout the seminar, over two dozen doctors were seen smoking outside the hall.
A sociologist commenting on this situation said lottery schemes for attracting professional doctors to the seminar, which was in fact a part of their education, were an eloquent commentary on the deterioration of society.
It was observed that a number of senior consultants i.e. professors, associate professors and assistant professors serving in the Punjab Medical College, including those who retired in the recent years, were conspicuous by their absence.
Most of the papers presented in the seminar were by Dr. Rana Mohsin who, in fact, seemed to be the motive force of the event. No worth mentioning office-bearer of the Pakistan Medical Association was seen active at the seminar.
Seminars and workshops play an important role in the dissemination of knowledge among the professionals and the ordinary citizens. The apathy of the medical professionals towards such a function is deplorable.
Speaking on the occasion, specialists warned that if steps were not taken to arrest the increasing rate of diabetes, the entire nation would have to pay a very high price in terms of impaired health. They said there were about seven million diabetics in the country, which was an alarmingly high number. Lack of awareness, disregard of preventive cure and poor dietary habits mainly contributed towards this high number. Awareness about the detrimental effects of the disease would help in its prevention and cure through timely treatment, remedial measures and scrupulous observance of doctor’s advice.
Underscoring the need for an advanced course with increasing frequency, speakers said the bulk of public care rested in the hands of overworked and under-informed general practitioners, adding that “education was not simply a part of treatment: it was the treatment”.
Enumerating the problems faced by general practitioners in the treatment of diabetes, they said it was a pity that there was no paramedical staff specially trained to look after the diabetics. They called upon the general practitioners to educate their patients about the early signs and symptoms of the disease so as to ensure timely advice to them at early stages.
They said with a little effort the general practitioners could enable the diabetics to monitor and check their sugar level, which would in turn help in checking the growth of diabetes-related complications in areas of ophthalmology, dermatology, surgery and cardio-vascular diseases.
They said: “In 25 per cent patients, vaginitis is a common complication of poorly-controlled diabetics. Vular itching or white thin to creamy discharge should alert the clinicians to the possible presence of diabetes. Necrobiosis lipoidica diabeticorum is prevalent in 0.3 per cent of diabetics. It is three times more common in women than men, characteristically found on the interior and lateral surfaces of the lower legs, face, arms and trunk. There may be one or several lesions either unilateral or bilateral. Lesions being as small, dusky red elevated nodules sharply circumscribed and slowly enlarge becoming a plaque irregular in outline, and is eventually depressed as the dermis becomes more atrophic. The colour becomes more brownish yellow except of the border, which remains red. The lesion may be anaesthetic due to destruction of cutaneous nerves.”
They said like all other complications of diabetes Mellitis, dealing with the occular complications was also teamwork. Neither ophthalmologists nor family physicians alone could deal with it. It needed proper initial assessment on the one hand and high-tech facilities on the other. The patient had more tendencies to develop blepharitis. Tear film abnormality led to dry eyes. Simple lubricant ointment served the purpose. Improvement of local hygiene had no substitute, they said.
According to speakers, monitoring erections that occur during sleep (nocturnal penile tumescence) can help rule out that certain causes of impotence are likely to be physical rather than psychological. Tests of nocturnal erections are not completely reliable. However, scientists have not standardized such tests and have not determined when they should be applied for best results. This means treating the primary cause is considered first. Psychotherapy and behaviour modifications are considered next.
A comprehensive and multidisciplinary approach is recommended for care of diabetic feet. Our patients are not fortunate enough to get all these specialized services due to a number of reasons, thus it will be cost-effective and patient friendly if foot complications of diabetes are prevented by general/family physician. The cornerstone of prevention policy is to recall a forgotten lesson of keen, clever and quick clinical examination of the foot which demands a few simple questions about patient’s habits about their feet and a few simple observations.
“The patients having developed a non-healing ulcer or infected ulcers, localized gangrene, frank gangrene and grade 1-5 diabetic foot along with systemic problems of diabetes like hypertension, ischaemic heart disease, nephropathy and retinopathy shall be referred to specialized centres. These are the patients who desperately require active involvement of surgical discipline. The colleagues in surgery are now constrained to adopt a range of procedures from limb preservation to amputations (life saving). The aim is to preserve as much of foot as possible for optimum ambulation”, they maintained.
They said a patient who had never experienced hypoglycemia practically had never been in good control. Frequent hypoglycemic symptoms requiring multiple unscheduled food intakes may be the underlying reasons for failure to lose weight. Moreover hypoglycemia was more dangerous in patients suffering from cardiovascular disease, in elderly and patients on concomitant B-blockers drugs and in those with hypoglycemic unawareness and autonomic neuropathy. Whenever an upward change in hypoglycemic drugs was prescribed, patients must be warned and reminded of possible hypoglycemic symptoms, they said.
Similarly, family members and colleagues along with the patients himself must be aware of the symptoms and the appropriate action in response well before drowsiness hampers the oral intake. Once oral intake is not possible attendants must be aware of buccal and rectral application of glucose containing pastes, and need to reach a medical facility. At the same time, doctors must be prepared to give intravenous glucose even if classical hypoglycemic symptoms are not present in a confused or unconscious patient. Giving few ampoules of 25 per cent glucose will cause no harm even to a hyperglycemic patient.
The seminar was attended by general practitioners of Faisalabad, Jhang, Toba Tek Sing and Sargodha, and presided over by Prof Dr. Altaf Husain Rathore and Prof Dr. Irshadul Haq.
Research papers were read by Dr. Muhammad Asim, Dr. Raja Mazhar Iqbal, Dr. Amir Chaudhry, Dr. Hashim Imran, Dr. Mohsin Rana, Dr. Akhtar Rasheed, Dr. Yousaf Hasan, Dr. Sohail Farooq and a number of other renowned professionals.


GST — a revenue at the cost of patient’s life
By Arshad Sharif
“MY mother must have it,” the young man cried. “She is suffering from a severe attack of asthma and we have run out of medicines.”
“I wish I could help,” said the pharmacist. “But the drug for asthma you are looking for is out of stock; there is a shortage”, he replied ruefully.
“Goddamn it”, the young man mumbled in desperation as he turned to leave the pharmacy.
The pharmacist shocked looked up, but the man was already out of the store, perhaps to check with the next drug store.
Feeling for someone’s suffering is perhaps easy enough to do, though it might do little to mitigate the distress of someone desperately looking for an asthma drug that has vanished from the market without a trace.
In many drug stores of the twin cities of Rawalpindi- Islamabad, similar situation is being encountered by those seeking essential medicines for treatment of heart ailments, acute epilepsy, high blood pressure and tranquillizers. They are either not available or are made available sporadically, but of course, way above the company price.
The reason, as revealed, by the pharmacists and wholesalers is the ensuing tug-of-war between the health authorities and drug distributors over imposition of the general sales tax (GST) and thus creating shortage of medicines in the market. A number of wholesalers said they had stopped buying new stocks of drugs with stamps of sales tax on them from distributors of pharmaceutical industry. The old stock has been consumed leading to shortage of many drugs, a wholesaler said.
Interviews revealed that several life saving drugs were in short supply in the market forcing patients to dole out extra bucks to buy them in black market, and at exorbitant costs.
Pharmaceutical industry leaders disclosed that the problem of essential drugs vanishing from the market is not uncommon, mainly because of a lopsided policy framework, that has over the years turned the country into a smugglers’ paradise for medicines, which are smuggled to the neighbouring countries at the expense of the patients, industry, and the exchequer. Yet the government has failed to check smuggling of drugs across the borders where they have a find a better market.
Research shows that last year, pharmaceutical and biotech companies in the United States alone spent over $30.3 billion on medicinal research. The year saw the US Food and Drug Administration (FDA) approve 32 new treatments, 24 drugs and 8 biologics including innovative treatments for AIDS, arthritis, cancer, glaucoma, heart disease, infectious diseases, schizophrenia, Alzheimer’s, migraines and other diseases.
The new medicines will help treat or prevent 32 diseases. According to an estimate, these will help American society save $250 billion a year in other healthcare costs as well as lost productivity and wages. Proportionate benefits will accrue to the rest of the world, including Third World countries, which cannot contribute directly to this process due to paucity of resources.
However, pharmaceutical industry leaders believe defective regulation and undue restrictions throttle investment in medical research and development in countries like Pakistan which is tantamount to arresting the pace of search for new cures. The logical result is the unmitigated suffering of the sick for want of cures, a doctor in an MNC said.
He said the situation is hardly conducive for developing a local research and development capability in Pakistan. Decades of wrong policies have distorted the market environment in unthinkable ways, he said.
The outcome of the myopic policy followed by the government has led to closure of nearly 80 pharmaceutical companies out of some 400 operating in the country over the last few years.
Explaining how the shortage of drugs is created in the market, industry sources said the price controls and regulations with imposition of taxes over the years lead to smuggling of drugs to neighbouring countries including India and burden on the industry.
Sources in the industry said by the end of 1999, pharmaceutical manufacturers were grappling with a cost increase of over 100 per cent from 1994.
The four factors leading to this stellar rise were an inflation of 97 per cent, rupee devaluation against the US dollar to the tune of 96 per cent, a 10 per cent custom’s duty imposed beginning July 1996, plus imposition in 1999 of 15 per cent sales tax on packaging materials, sources said.
Moreover, the pharmaceutical manufacturers are struggling to keep their nose above the water in the face of a broad range of market access barriers and deficiencies in intellectual property protection, sources said.
Contrary to the reasons given by the industry leaders for drug shortage, officials believe majority of multinational pharmaceutical companies create artificial demand for drugs on the pretext of shortage of raw materials and taxes to mint extra profits.
With negotiations between the health ministry and the pharmaceutical industry on for resolving the row over the newly imposed GST, the black marketeers are minting money by capitalising on patient’s miseries. Insiders said Dalintin tablets used in acute cases of epilepsy, sometimes fetch a price tag of Rs500 per 100 tablets as compared to the company price of around Rs50 per 100 tablets.
Lescol, a capsule for treating high blood pressure, which sells for around Rs540 is not available in the market at present at any price. The widely used Buscopan, a tablet manufactured locally by some MNCs, is in short supply and selling at almost three times the original price in the black market.
Tryptanol, Angesid, Thyroxin, Inderal, Zextrol, Ventloin, and many other drugs are in short supply, a retailer said.

